ARCALYST® (rilonacept) OFFERS HIGH COMMERCIAL ACCESS WITH LOW OUT-OF-POCKET COST

A significant majority of PA requests for ARCALYST have been approved*†

Eligible, commercially insured patients pay as little as $0 per month for ARCALYST treatment with the copay assistance program*

From approval in March 2021 to September 2024. | *Based on final coverage approval.

Payer Coverage Decision Example

This is an example of common payer coverage decision making; however, each payer may differ in the determination of coverage for ARCALYST. Please refer to specific payer policies on ARCALYST access requirements.

Prior Authorization (PA) Best Practices

Prevent delays with ARCALYST initiation

The information needed for the ARCALYST Enrollment Form is similar to the information needed for the PA documentation. Filling out both forms and submitting at the same time may help to:

  • Potentially accelerate the time for a patient to gain access and initiate ARCALYST
  • Save you and your staff time since the patient’s file is already available when your office is filling out the Enrollment Form

Prior authorization helpful hint

In the PA form, as allowed, include previous medications used to treat recurrent pericarditis such as NSAIDs, colchicine, and/or steroids.

Use CoverMyMeds® to assist your team with PAs

Sign up for free at www.covermymeds.health

CoverMyMeds will automate the PA process to make completing, reviewing, and tracking PA requests quicker and easier. 

If you have any questions about CoverMyMeds, please ask your Patient Access Lead or call any member of the Kiniksa OneConnect™ program team.

Download the User Guide: The Kiniksa OneConnect™ Program Through CoverMyMeds

This guide outlines the required steps and helpful suggestions for completing PAs to help speed the coverage determination process for your patients prescribed ARCALYST.

Download User Guide

Call the Kiniksa OneConnect™ program at 1-833-546-4572, Option 1, if you have any questions about submitting PAs for ARCALYST through CoverMyMeds.

Payer Access Resources

Letter of Medical Necessity Guide and Template
ARCALYST Access & Reimbursement Guide
Payer Coverage Flow
Appeal Letter Guide and Template
CoverMyMeds User Guide for ARCALYST

Supporting your practice in navigating access for your patients

The Kiniksa OneConnect™ program is designed to support you throughout the access process in order to help your patients initiate their treatment quickly. In addition to benefits verification and providing Prior Authorization and Appeals support, your dedicated Patient Access Lead can identify financial assistance programs to help make access to treatment more affordable for eligible patients.

Call 1-833-KINIKSA (1-833-546-4572), Option 1
Monday-Friday (8 AM – 8 PM ET)

Request to speak to a Clinical Sales Specialist

Indication

ARCALYST® (rilonacept) is an interleukin-1 blocker indicated for:

  • Treatment of recurrent pericarditis (RP) and reduction in risk of recurrence in adults and pediatric patients 12 years and older.
  • Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome (FCAS), and Muckle-Wells Syndrome (MWS) in adults and children 12 years and older. 
  • Maintenance of remission of Deficiency of Interleukin-1 Receptor Antagonist (DIRA) in adults and pediatric patients weighing 10 kg or more.

Important Safety Information

Warnings and Precautions

  • Interleukin-1 (IL-1) blockade may interfere with the immune response to infections. Treatment with another medication that works through inhibition of IL-1 or inhibition of tumor necrosis factor (TNF) is not recommended as this may increase the risk of serious infection. Serious, life-threatening infections have been reported in patients taking ARCALYST. Do not initiate treatment with ARCALYST in patients with an active or chronic infection.
  • Discontinue ARCALYST if a patient develops a serious infection.
  • It is possible that taking drugs such as ARCALYST that block IL-1 may increase the risk of tuberculosis (TB) or other atypical or opportunistic infections.
  • Although the impact of ARCALYST on infections and the development of malignancies is not known, treatment with immunosuppressants, including ARCALYST, may result in an increase in the risk of malignancies.
  • Hypersensitivity reactions associated with ARCALYST occurred in clinical trials. Discontinue ARCALYST and initiate appropriate therapy if a hypersensitivity reaction occurs. 
  • Increases in non-fasting lipid profile parameters occurred in patients treated with ARCALYST in clinical trials. Patients should be monitored for changes in their lipid profiles.
  • Since no data are available, avoid administration of live vaccines while patients are receiving ARCALYST. ARCALYST may interfere with the normal immune response to new antigens, so vaccines may not be effective in patients receiving ARCALYST. It is recommended that, prior to initiation of therapy with ARCALYST, patients receive all recommended vaccinations, as appropriate.

Adverse Reactions

  • In patients with CAPS or RP, the most common adverse reactions (≥10%) include injection-site reactions and upper respiratory tract infections.
  • In patients with DIRA, the most common adverse reactions (>10%) include upper respiratory tract infections, rash, otitis media, pharyngitis, and rhinorrhea.

Drug Interactions

  • In patients being treated with CYP450 substrates with narrow therapeutic indices, therapeutic monitoring of the effect or drug concentration should /pi.pdfbe performed, and the individual dose of the medicinal product may need to be adjusted.

For more information about ARCALYST, see full Prescribing Information.